AVSAR TABLET 5/160 MG 2X7S

Amlodipine, a calcium channel blocker, works by relaxing arterial walls and enhancing blood flow through the inhibition of calcium ion influx in vascular smooth muscle cells. In contrast, valsartan is an angiotensin II receptor blocker (ARB) that lowers blood pressure by preventing vasoconstriction and reducing aldosterone secretion. When co-formulated, these two agents deliver a complementary mechanism of action, with amlodipine targeting calcium-mediated vascular tension and valsartan modulating the renin-angiotensin system. This dual approach achieves superior blood pressure control compared to monotherapy, making the combination highly effective for managing hypertension.